Comprehensive research information for laboratory professionals
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed as an analog of the endogenous immunomodulatory peptide tuftsin. It was designed at the Institute of Molecular Genetics, Russian Academy of Sciences, by elongating the tuftsin sequence with Pro-Gly-Pro to enhance metabolic stability . Researchers study Selank for its effects on the GABAergic system, neurotrophin expression, and stress-response cytokine profiles. Unlike classical benzodiazepines, Selank does not cause amnesia, withdrawal, or dependence in preclinical models, making it a unique reference compound for anxiety and stress research.