Selank Research Highlights & Key Studies

Selank has been extensively studied in unpredictable chronic mild stress (UCMS) models, where it reduced anxiety indicators in rats exposed to prolonged stress . Gene expression studies have identified Selank-induced changes in Drd1a, Drd2, and Hcrt genes, suggesting effects on dopamine signaling and sleep-wake regulation . Researchers have also explored Selank's effects on neurotrophin transcription in ischemic cortex models, observing upregulation of BDNF and Trk receptor expression.